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1

Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

David B. Ramsden, Philip W.-L. Ho, Jessica W.-M. Ho, Hui-Fang Liu, Danny H.-F. So, Ho-Man Tse, Koon-Ho Chan, Shu-Leong Ho

Journal:

Brain and Behavior

Year:

2012

Language:

english

File:

PDF, 320 KB

english, 2012

2

Ischemic stroke related to intracranial branch atheromatous disease and comparison with large and small artery diseases

May Wai-Mei Kwan, Windsor Mak, Raymond Tak-Fai Cheung, Shu-Leong Ho

Journal:

Journal of the Neurological Sciences

Year:

2011

Language:

english

File:

PDF, 182 KB

english, 2011

3

Burden of rare variants in ALS genes influences survival in familial and sporadic ALS

Pang, Shirley Yin-Yu, Hsu, Jacob Shujui, Teo, Kay-Cheong, Li, Yan, Kung, Michelle H.W., Cheah, Kathryn S.E., Chan, Danny, Cheung, Kenneth M.C., Li, Miaoxin, Sham, Pak-Chung, Ho, Shu-Leong

Journal:

Neurobiology of Aging

Year:

2017

Language:

english

File:

PDF, 696 KB

english, 2017

4

−459C>T point mutation in 5′ non-coding region of human GJB1 gene is linked to X-linked Charcot-Marie-Tooth neuropathy

Miaoxin Li, Tat-Sun Cheng, Philip W.-L. Ho, Koon-Ho Chan, Windsor Mak, Raymond T.-F. Cheung, David B. Ramsden, Pak-Chung Sham, Youqiang Song, Shu-Leong Ho

Journal:

Journal of the Peripheral Nervous System

Year:

2009

Language:

english

File:

PDF, 262 KB

english, 2009

5

Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease

Philip WL Ho, Jessica WM Ho, Hui-Fang Liu, Danny HF So, Zero HM Tse, Koon-Ho Chan, David B Ramsden, Shu-Leong Ho

Journal:

Translational Neurodegeneration

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

6

Multimodal MRI of the hippocampus in Parkinson’s disease with visual hallucinations

Yao, Nailin, Cheung, Charlton, Pang, Shirley, Shek-kwan Chang, Richard, Lau, Kui Kai, Suckling, John, Yu, Kevin, Ka-Fung Mak, Henry, Chua, Siew Eng, Ho, Shu-Leong, McAlonan, Grainne M.

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

2016

Language:

english

File:

PDF, 1.89 MB

english, 2016

7

Transcriptional regulation of UCP4 by NF-κB and its role in mediating protection against MPP+ toxicity

Jessica Wing-Man Ho, Philip Wing-Lok Ho, Wei-Yi Zhang, Hui-Fang Liu, Ken Hon-Hung Kwok, David Chi-Wai Yiu, Koon-Ho Chan, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 1.88 MB

english, 2010

8

PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion

Ho, Philip Wing-Lok, Pang, Shirley Yin-Yu, Li, Miaoxin, Tse, Zero Ho-Man, Kung, Michelle Hiu-Wai, Sham, Pak-Chung, Ho, Shu-Leong

Journal:

Brain and Behavior

Year:

2015

Language:

english

File:

PDF, 523 KB

english, 2015

9

Oral stereognosis in stroke and Parkinson's disease: a comparison of partially dentate and edentulous individuals

Edmond H. Pow, Katherine C. Leung, Anne S. McMillan, May C. Wong, Leonard S. Li, Shu-Leong Ho

Journal:

Clinical Oral Investigations

Year:

2001

Language:

english

File:

PDF, 41 KB

english, 2001

10

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase.

Lis, Pawel, Burel, Sophie, Steger, Martin, Mann, Matthias, Brown, Fiona, Diez, Federico, Tonelli, Francesca, Holton, Janice L., Ho, Philip Winglok, Ho, Shu-Leong, Chou, Meng-Yun, Polinski, Nicole K, M

Journal:

Biochemical Journal

Year:

2017

Language:

english

File:

PDF, 1.85 MB

english, 2017

11

Abnormal diffusion tensor in nonsymptomatic familial amyotrophic lateral sclerosis with a causative superoxide dismutase 1 mutation

Man-Cheuk Ng, Jenny Ting Ho, Shu-Leong Ho, Raymand Lee, Geng Li, Tat-Sun Cheng, You-Qiang Song, Philip Wing-Lok Ho, Gardian Chung-Yan Fong, Windsor Mak, Koon-Ho Chan, Leonard Sheung-Wai Li, Keith Dip-

Journal:

Journal of Magnetic Resonance Imaging

Year:

2008

Language:

english

File:

PDF, 146 KB

english, 2008

12

Methyl-4-phenylpyridinium ion modulates expression of mitochondrial uncoupling proteins 2, 4, and 5 in catecholaminergic (SK-N-SH) cells

Philip Wing-Lok Ho, David Yiu-Leung Chan, Ken Hon-Hung Kwok, Andrew Chi-Yuen Chu, Jessica Wing-Man Ho, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho

Journal:

Journal of Neuroscience Research

Year:

2005

Language:

english

File:

PDF, 1.31 MB

english, 2005

13

Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP+Toxicity in Neuronal Cells

Philip Wing-Lok Ho, Hui-Fang Liu, Jessica Wing-Man Ho, Wei-Yi Zhang, Andrew Chi-Yuen Chu, Ken Hon-Hung Kwok, Xuan Ge, Koon-Ho Chan, David Boyer Ramsden, Shu-Leong Ho

Journal:

Neurotoxicity Research

Year:

2010

Language:

english

File:

PDF, 493 KB

english, 2010

14

COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice

Feng, Zhehui, Li, Dongdong, Fung, Peter C. W., Pei, Zhong, Ramsden, David B., Ho, Shu-Leong

Journal:

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

15

Distribution of catechol-O-methyltransferase expression in human central nervous system

Hong, Jiang, Shu-Leong, Ho, Tao, Xie, Lap-Ping, Young

Journal:

Year:

1998

Language:

english

File:

PDF, 400 KB

english, 1998

16

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

Liu, Hui-Fang, Ho, Philip Wing-Lok, Leung, Gideon Chi-Ting, Lam, Colin Siu-Chi, Pang, Shirley Yin-Yu, Li, Lingfei, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.40 MB

english, 2017

17

Induction of unspliced c-fos messenger RNA in rodent brain by kainic acid and lipopolysaccharide

Zhehui Feng, Ling-Yuan Kong, Qiping Qi, Shu-Leong Ho, Ningyi Tiao, Guoying Bing, Yi-Fan Han

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 320 KB

english, 2001

18

UCP4 is a target effector of the NF-κB c-Rel prosurvival pathway against oxidative stress

Jessica Wing-Man Ho, Philip Wing-Lok Ho, Hui-Fang Liu, Danny Hon-Fai So, Koon-Ho Chan, Zero Ho-Man Tse, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

19

Can clubbing tell you about ears?

Richard SK Chang, Macy MS Lui, David CL Lam, Raymond TF Cheung, Shu-Leong Ho

Journal:

Year:

2009

Language:

english

File:

PDF, 159 KB

english, 2009

20

Cytochrome P4502D6 (debrisoquine 4-hydroxylase) and Parkinson's disease in Chinese and Caucasians

Shu-Leong Ho, Michelle H.W. Kung, Leonard S.W. Li, Ian J. Lauder, David B. Ramsden

Journal:

European Journal of Neurology

Year:

1999

File:

PDF, 862 KB

1999

21

High-grade lymphoma after azathioprine treatment for Vogt-Kaganayi-Harada syndrome

Hon, Charmaine, Ho, Shu-Leong, Ma, Edmond, Trendell-Smith, Nigel, Au, Wing

Journal:

Leukemia and Lymphoma

Year:

2005

Language:

english

File:

PDF, 1.47 MB

english, 2005

22

Translation and validation of the standard Chinese version of PDQ-39: A quality-of-life measure for patients with Parkinson's disease

Kin-Lun Tsang, Iris Chi, Shu-Leong Ho, Vivian Weiqun Lou, Tatia M.C. Lee, Leung-Wing Chu

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

23

Estrogen therapy in postmenopausal women with Parkinson’s disease

Tsang, Kin-Lun, Ho, Shu-Leong

Journal:

Expert Review of Neurotherapeutics

Year:

2001

Language:

english

File:

PDF, 100 KB

english, 2001

24

LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity

Liu, Hui-Fang, Lu, Song, Ho, Philip Wing-Lok, Tse, Ho-Man, Pang, Shirley Yin-Yu, Kung, Michelle Hiu-Wai, Ho, Jessica Wing-Man, Ramsden, David B., Zhou, Zhong-Jun, Ho, Shu-Leong

Journal:

Annals of Clinical and Translational Neurology

Year:

2014

Language:

english

File:

PDF, 576 KB

english, 2014

25

Predicting Mendelian Disease-Causing Non-Synonymous Single Nucleotide Variants in Exome Sequencing Studies

Li, Miao-Xin, Kwan, Johnny S. H., Bao, Su-Ying, Yang, Wanling, Ho, Shu-Leong, Song, Yong-Qiang, Sham, Pak C., MacArthur, Daniel G.

Journal:

Year:

2013

Language:

english

File:

PDF, 622 KB

english, 2013

26

Single-nucleotide polymorphism of transient axonal glycoprotein-1 and its correlation with clinical features and prognosis in chronic inflammatory demyelinating polyneuropathy

Shirley Y. Y. Pang, Koon-Ho Chan, Windsor W. W. Mak, Michelle H. W. Kung, Chi-Nam Lee, Tak-Hong Tsoi, Edwin K. K. Yip, Shu-Leong Ho

Journal:

Journal of the Peripheral Nervous System

Year:

2012

Language:

english

File:

PDF, 439 KB

english, 2012

27

PMCA4 (ATP2B4) Mutation in Familial Spastic Paraplegia

Li, Miaoxin, Ho, Philip Wing-Lok, Pang, Shirley Yin-Yu, Tse, Zero Ho-Man, Kung, Michelle Hiu-Wai, Sham, Pak-Chung, Ho, Shu-Leong, Seaman, Matthew

Journal:

Year:

2014

Language:

english

File:

PDF, 385 KB

english, 2014

28

Prognostic implications of surrogate markers of atherosclerosis in low to intermediate risk patients with Type 2 Diabetes

Kui-Kai Lau, Yuen-Kwun Wong, Yap-Hang Chan, Kai-Hang Yiu, Kay-Cheong Teo, Leonard Sheung-Wai Li, Shu-Leong Ho, Koon-Ho Chan, Chung-Wah Siu, Hung-Fat Tse

Journal:

Cardiovascular Diabetology

Year:

2012

Language:

english

File:

PDF, 219 KB

english, 2012

29

Resting activity in visual and corticostriatal pathways in Parkinson's disease with hallucinations

Yao, Nailin, Pang, Shirley, Cheung, Charlton, Chang, Richard Shek-kwan, Lau, Kui Kai, Suckling, John, Yu, Kevin, Mak, Henry Ka-Fung, McAlonan, Grainne, Ho, Shu-Leong, Chua, Siew-eng

Journal:

Parkinsonism & Related Disorders

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

30

Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas

Salama A. Salama, Shu-Leong Ho, Hui-Qun Wang, Jukka Tenhunen, Carola Tilgmann, Ayman Al-Hendy

Journal:

Fertility and Sterility

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

31

Monoamine oxidase-B (MAO-B) inhibitors: implications for disease-modification in Parkinson’s disease

Teo, Kay, Ho, Shu-Leong

Journal:

Translational Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 263 KB

english, 2013

32

Visuomotor control in patients with Parkinson's disease

Chen, Jing, Ho, Shu-Leong, Lee, Tatia Mei-Chun, Chang, Richard Shek-Kwan, Pang, Shirley Yin-Yu, Li, Li

Journal:

Neuropsychologia

Year:

2016

Language:

english

File:

PDF, 870 KB

english, 2016

33

Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality

Lau, Kui-Kai, Wong, Yuen-Kwun, Teo, Kay-Cheong, Chang, Richard Shek-Kwan, Hon, Sonny Fong-Kwong, Chan, Koon-Ho, Cheung, Raymond Tak-Fai, Li, Leonard Sheung-Wai, Tse, Hung-Fat, Ho, Shu-Leong, Siu, Chun

Journal:

Year:

2014

Language:

english

File:

PDF, 247 KB

english, 2014

34

Emotion recognition in patients with idiopathic Parkinson's disease

James T.H. Yip, Tatia M.C. Lee, Shu-Leong Ho, Kin-Lun Tsang, Leonard S.W. Li

Journal:

Movement Disorders

Year:

2003

Language:

english

File:

PDF, 77 KB

english, 2003

35

Knockdown of uncoupling protein-5 in neuronal SH-SY5Y cells: Effects on MPP+-induced mitochondrial membrane depolarization, ATP deficiency, and oxidative cytotoxicity

Philip Wing-Lok Ho, Andrew Chi-Yuen Chu, Ken Hon-Hung Kwok, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 475 KB

english, 2006

36

Manganese-enhanced MRI detection of neurodegeneration in neonatal hypoxic-ischemic cerebral injury

Jian Yang, Pek-Lan Khong, Yanxin Wang, Andrew Chi-Yuen Chu, Shu-Leong Ho, Pik-To Cheung, Ed X. Wu

Journal:

Magnetic Resonance in Medicine

Year:

2008

Language:

english

File:

PDF, 3.26 MB

english, 2008

37

Efficient attenuation of Friedreich's ataxia (FRDA) cardiomyopathy by modulation of iron homeostasis-human induced pluripotent stem cell (hiPSC) as a drug screening platform for FRDA

Lee, Yee-Ki, Lau, Yee-Man, Ng, Kwong-Man, Lai, Wing-Hon, Ho, Shu-Leong, Tse, Hung-Fat, Siu, Chung-Wah, Ho, Philip Wing-Lok

Journal:

International Journal of Cardiology

Year:

2016

Language:

english

File:

PDF, 937 KB

english, 2016

38

Revealing ecological risks of priority endocrine disrupting chemicals in four marine protected areas in Hong Kong through an integrative approach

Xu, Elvis Genbo, Ho, Philip Wing-Lok, Tse, Zero, Ho, Shu-Leong, Leung, Kenneth Mei Yee

Journal:

Environmental Pollution

Year:

2016

Language:

english

File:

PDF, 1.96 MB

english, 2016

39

Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)

Ho, Philip Wing-Lok, Leung, Chi-Ting, Liu, Huifang, Pang, Shirley Yin-Yu, Lam, Colin Siu-Chi, Xian, Jiawen, Li, Lingfei, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong

Journal:

Year:

2019

File:

PDF, 5.18 MB

2019

40

G209A Mutation in the α-synuclein gene is rare and not associated with sporadic Parkinson's disease

Dr. Shu-Leong Ho, Michelle H. W. Kung

Journal:

Movement Disorders

Year:

1998

Language:

english

File:

PDF, 251 KB

english, 1998

41

Characterization and Implications of Estrogenic Down-Regulation of Human Catechol- O -Methyltransferase Gene Transcription

Xie, Tao, Ho, Shu-Leong, Ramsden, David

Journal:

Molecular Pharmacology

Year:

1999

Language:

english

File:

PDF, 262 KB

english, 1999

42

Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity

Ken Hon-Hung Kwok, Philip Wing-Lok Ho, Andrew Chi-Yuen Chu, Jessica Wing-Man Ho, Hui-Fang Liu, David Chi-Wai Yiu, Koon-Ho Chan, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 789 KB

english, 2010

43

Catechol-O-methyltransferase inhibitors in Parkinson's disease

Tao Xie, Shu-Leong Ho, David Ramsden

Journal:

Year:

1998

Language:

english

File:

PDF, 46 KB

english, 1998

44

Mitochondrial UCP4 attenuates MPP+- and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression

Andrew Chi-Yuen Chu, Philip Wing-Lok Ho, Ken Hon-Hung Kwok, Jessica Wing-Man Ho, Koon-Ho Chan, Hui-Fang Liu, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu-Leong Ho

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 1.26 MB

english, 2009

45

Antiplatelet Resumption after Antiplatelet-Related Intracerebral Hemorrhage: A Retrospective Hospital-Based Study

Teo, Kay-Cheong, Lau, Gary K.K., Mak, Ryan H.Y., Leung, Ho-Yan, Chang, Richard S.K., Tse, Man-Yu, Lee, Raymand, Leung, Gilberto K.K., Ho, Shu-Leong, Cheung, Raymond T.F., Siu, David C.W., Chan, Koon-H

Journal:

World Neurosurgery

Year:

2017

Language:

english

File:

PDF, 2.36 MB

english, 2017

46

The role of gene variants in the pathogenesis of neurodegenerative disorders as revealed by next generation sequencing studies: a review

Pang, Shirley Yin-Yu, Teo, Kay-Cheong, Hsu, Jacob Shujui, Chang, Richard Shek-Kwan, Li, Miaoxin, Sham, Pak-Chung, Ho, Shu-Leong

Journal:

Translational Neurodegeneration

Year:

2017

Language:

english

File:

PDF, 440 KB

english, 2017

47

Acute Epiglottitis And Chloraseptic

Shu-Leong Ho and K. Hollinrake

Journal:

Year:

1989

Language:

english

File:

PDF, 398 KB

english, 1989

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